持续性急性呼吸窘迫综合征(ARDS)的特点是进行性炎症反应、长期机械通气、过度纤维增生和高病死率。曾有报道说糖皮质激素可提高该病生存率,最近美国学者进行了一项多中心随机对照的临床试验来验证了这一观点。该试验采用双盲法纳入了180例ARDS患者,所有患者均服用甲基泼尼松或 Persistent acute respiratory distress syndrome (ARDS) is characterized by progressive inflammatory response, long-term mechanical ventilation, excessive fibrosis and high mortality. It has been reported that glucocorticoids can improve the survival rate of the disease, the United States recently conducted a multi-center randomized controlled clinical trial to verify this view. The trial enrolled 180 patients with ARDS using a double-blind approach, all with either methylprednisone or