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目的:观察痉挛型脑瘫合并癫痫患儿经妥泰/托吡酯治疗后肢体肌张力和关节活动度的改善情况。方法:随机将痉挛型脑瘫合并癫痫患儿分为对照组28例和观察组20例,观察组给予妥泰/托吡酯,其余治疗措施两组相同。分别于治疗前、治疗后半年对患儿进行肌张力评级,测量髋关节被动屈曲角度、膝关节被动屈曲角度。结果:对照组和观察组患儿的肌张力、髋关节、膝关节的改善效率两组比较差异有统计学意义(P<0.05),说明经妥泰/托吡酯治疗后患儿肌张力以及髋关节、膝关节活动度改善情况明显优于对照组。结论:应用妥泰/托吡酯治疗能够在短时间内降低痉挛型脑瘫患儿的肌张力,增加关节活动度,为中医推拿及功能训练打下良好基础,减轻患儿康复训练中的痛苦,充分体现中西医药整体化治疗的优势。
Objective: To observe the improvement of limb muscle tension and joint mobility in children with spastic cerebral palsy and epilepsy after topiramate / topiramate treatment. Methods: Children with spastic cerebral palsy and epilepsy were randomly divided into control group (n = 28) and observation group (n = 20). The observation group was treated with topiramate and topiramate. The rest of the treatment measures were the same in both groups. Respectively before treatment, six months after treatment of children with muscle tone rating, measured passive hip flexion angle, knee passive flexion angle. Results: There was significant difference between the control group and the observation group in muscle tone, hip joint and knee joint in improving efficiency (P <0.05), indicating that the hyperthyroidism and the hip joint The improvement of knee mobility was obviously better than that of the control group. Conclusion: Topiramate / topiramate treatment can reduce the muscle tension and increase the joint mobility in children with spastic cerebral palsy in a short period of time, lay a good foundation for TCM massage and functional training and relieve the pain in children’s rehabilitation training, The advantages of medical holistic treatment.