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作者对HBsAg阳性母亲所生的898名健康足月婴儿(男453人,女445人)以减量方案给予被动-自动免疫,即出生8小时内注射1剂超免疫球蛋白,20日龄接种首剂乙型肝炎疫苗,2月后接种第2剂,12月龄时给予加强接种。对98名幼儿随访5年,第60个月时测定抗-HBs,其中11名于第2剂后抗-HBs应答良好者抗-HBs转阴。经第2剂加强
The authors gave 898 healthy full-term infants (453 males and 445 females) born to HBsAg-positive mothers in a passive-autoimmune manner with a reduction regimen of 1 immunoglobulin injection within 8 hours of birth and 20 days of vaccination The first dose of hepatitis B vaccine, 2 months after the second dose, 12 months to give enhanced vaccination. 98 children were followed up for 5 years and anti-HBs were measured at the 60th month. Eleven of the 11 anti-HBs turned negative after anti-HBs response after the second dose. The second agent to strengthen