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目的观察凉血止血法对小儿紫癜风血热风盛型的临床疗效。方法将162例过敏性紫癜患儿分为观察组83例和对照组79例。对照组采用西医常规用药氯苯那敏、西咪替丁;观察组在常规用药基础上服用自拟方,每日1付,水煎服。两组均治疗4周。观察并记录两组患儿的临床疗效、症状积分、血浆D-二聚体数值、复发率。结果观察组总有效率为97.59%,对照组总有效率为75.95%,两组有统计学差异(P<0.05);观察组治疗后症状积分为2.21±0.12,对照组为2.32±0.11,观察组低于对照组,差异具有统计学意义(P<0.05);观察组治疗后D-D数值为0.20±0.11,对照组为0.22±0.13,两组差异无统计学意义(P>0.05);观察组复发率为8.43%,对照组为29.11%,观察组明显低于对照组,差异有统计学意义(P<0.05)。结论凉血止血法治疗小儿紫癜风血热风盛型临床疗效确切,并可降低患者D-D,改善血液高凝状态,降低复发率。
Objective To observe the clinical efficacy of cooling blood and stopping bleeding on children with purpura. Methods 162 cases of children with Henoch-Schonlein purpura were divided into observation group (n = 83) and control group (n = 79). The control group used conventional western medicine chlorphenamine, cimetidine; observation group on the basis of conventional medication taking self-prepared side, 1 day, Shuijianbi. Both groups were treated for 4 weeks. The clinical efficacy, symptom score, plasma D-dimer value and recurrence rate were observed and recorded in both groups. Results The total effective rate was 97.59% in the observation group and 75.95% in the control group, with statistical significance (P <0.05). The symptom score of the observation group after treatment was 2.21 ± 0.12 and that of the control group was 2.32 ± 0.11 (P <0.05). The DD value of the observation group was 0.20 ± 0.11 after treatment and 0.22 ± 0.13 in the control group, with no significant difference between the two groups (P> 0.05). The observation group The recurrence rate was 8.43% in the control group and 29.11% in the control group, the observation group was significantly lower than the control group, the difference was statistically significant (P <0.05). Conclusion Cooling blood hemostatic method for treatment of purpura in children with blood-hot Sheng Sheng clinically effective and can reduce the D-D, improve blood hypercoagulability and reduce the recurrence rate.