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用免疫放射分析法(IRMA)测定甲状腺机能亢进(甲亢),甲状腺机能减退(甲减),甲亢控制,非甲状腺疾病患者及正常人的血清TSH.结果:甲亢组(±s)为0.074±0.043mIU·L-1,甲减组为66.199±49.52mIU·L-1,与其他各组有极显著差异(P<0.01).甲亢最低值为0.011,甲减最高值为150,示IRMA灵敏度很高,可测范围很宽.TSH(IRMA)在甲亢及甲减组的诊断符合率均为100%,尤对早期亚临床型甲功异常有重要诊断价值,应作为甲功测定的一线指标,甲亢控制组TSH(IRMA)恢复正常最晚,对指导药物治疗意义不大,非甲状腺疾病组9.68%与甲亢组值交叉,正常组4.10%假阳性.
Serum TSH levels in patients with hyperthyroidism, hypothyroidism (hypothyroidism), hyperthyroidism control, non-thyroid disease and normal controls were determined by immuno-radiometric assay (IRMA). Results: The hyperthyroidism group (± s) was 0.074 ± 0.043mIU · L-1, and the hypothyroidism group was 66.199 ± 49.52mIU · L-1, which was significantly different from other groups (P <0.05). 01). The lowest value of hyperthyroidism is 0.011, the highest value of hypothyroidism is 150, which shows the high sensitivity of IRMA and the measurable range is very wide. The coincidence rate of TSH (IRMA) in hyperthyroidism and hypothyroidism was 100%, especially for early subclinical thyroid dysfunction. It should be used as a first-line index of thyroid function test, and TSH (IRMA) recovery in hyperthyroidism control group Normal late, little significance for the guidance of drug treatment, non-thyroid disease group 9.68% and hyperthyroidism group value cross, normal group 4.10% false positive.