同种抗体引起的新生儿溶血病(HDN)一般有三个血清学反应特征:母亲血清中可检测到IgG同种抗体;婴儿红细胞直接抗球蛋白试验(DAT)阳性,以及婴儿红细胞洗脱液中含有引起HDN的特异性IgG同种抗体。发生HDN而婴儿红细胞DAT呈阴性或弱阳性的报道颇为少见,但在ABO新生儿溶血病中却曾有过报道。因此,认为DAT是临床上诊断HDN的一项极其可靠的预测指标,尤其是在ABO系统相容的情况下,更 Hemolytic hemolytic disease (HDN) caused by alloantibodies generally has three serological features: IgG alloantibodies detectable in maternal serum; infantile erythrocyte direct antiglobulin test (DAT) positive, and infant erythrocyte eluate Contains HDN-specific IgG allo-antibodies. HDN occurs and infant erythrocyte DAT negative or weak positive reports are quite rare, but ABO neonatal hemolytic disease has been reported. Therefore, it is considered that DAT is an extremely reliable predictor of clinically diagnosing HDN, especially when the ABO system is compatible