放射性粒子(125)~I组织间插置放疗对肺癌的影响及作用机制(英文)

来源 :The Chinese-German Journal of Clinical Oncology | 被引量 : 0次 | 上传用户:jayexxfu1
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Objective:The aim of this study was to evaluate effect and mechanism of 125I radioactive particles interposed radiotherapy between organizations on lung cancer.Methods:Fourteen cases of patients diagnosed with non-small cell lung cancer(NSCLC),the use of the B-,CT-guided,according to preoperative imaging and treatment planning system(TPS) program for radioactive particles interposed 125I interstitial radiotherapy.Results:All patients were successfully 125I interstitial radioactive particles interposed radiotherapy.Postoperative local complete tumor remission in 9 cases,partial remission in 5 cases,the efficiency of 100%.No case of serious complications.After 3 to 4 weeks of chemotherapy after 11 cases.4 cases of lung cancer with bone metastases,pain completely disappeared after treatment.Up to now,five cases have died due to tumor progression,survival time of 12 to 16 months.Nine cases still under follow-up observation and treatment.Conclusion:125 I radioactive particles interposed radiotherapy between organizations of lung cancer,simple operation,trauma,fewer complications,conformal high,high local tumor dose,efficacy,and is a supplement of modern radiotherapy techniques for the treatment of lung cancer provides a comprehensive line of the method of effective. Objective: The aim of The study was to evaluate effect and mechanism of 125I radioactive particles interposed radiotherapy between organizations on lung cancer. Methods: Fourteen cases of patients diagnosed with non-small cell lung cancer (NSCLC), the use of the B- CT-guided, according to preoperative imaging and treatment planning system (TPS) program for radioactive particles 125I interstitial radiotherapy. Results: All patients were successfully 125I interstitial radioactive particles preferred radiotherapy. Postoperative local complete tumor remission in 9 cases, partial remission in 5 Cases, the efficiency of 100% .No case of serious complications. After 3 to 4 weeks of chemotherapy after 11 cases.4 cases of lung cancer with bone metastases, pain completely disappeared after treatment.Up to now, five cases have died due to tumor progression, survival time of 12 to 16 months. Nine cases still under follow-up observation and treatment. Confclusion: 125 I radioactive particles is rad iotherapy between organizations of lung cancer, simple operation, trauma, fewer complications, conformal high, high local tumor dose, efficacy, and is a supplement of modern radiotherapy techniques for the treatment of lung cancer provide a comprehensive line of the method of effective.
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