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目的：探讨活体亲属肾移植的安全性、可行性，并评价亲属肾移植的临床效果。 方法：通过对１２例活体亲属肾移植的观察、复习文献资料，并对供者的术前准备、手术特点及免疫抑制剂的应用进行研究。 结果：１２ 例供者均无并发症出现，术后７～９ 天出院。１ 例受者出现移植肾功能延迟恢复；１ 例受者出现急性排斥，应用激素冲击治疗三天后逆转。所有受者肾功能均恢复良好。随访满６ 个月的６ 例受者，其平均ＢＵＮ、ＳＣｒ 和肌酐清除率分别为８－２ ｍ ｍｏｌ／Ｌ、９７－２ μｍｏｌ／Ｌ和９１ ｍｌ／ｍｉｎ。 结论：活体亲属供肾是安全可行的。受者的人／肾存活率优于尸体供者。活体亲属肾移植是扩大供肾来源、救治大量尿毒症患者的较好方法。
Objective: To investigate the safety and feasibility of living-related renal transplantation and to evaluate the clinical effect of renal transplantation in relatives. Methods: 12 cases of living relatives kidney transplantation observation, review of literature, and donor donor preoperative preparation, operation characteristics and immunosuppressant application research. Results: All 12 donors showed no complications and were discharged from 7 to 9 days after operation. One patient had delayed graft function recovery; one patient developed acute rejection and was reversed after three days of treatment with hormonal shock. Renal function recovered well in all recipients. Six patients who were followed up for 6 months had average BUN, SCr and creatinine clearance of 8-2 m mol / L, 97-2 μmol / L and 91 ml / min, respectively. Conclusion: Living relatives donor kidney is safe and feasible. Recipient’s / kidney survival rate is superior to the cadaver donor. Living relatives kidney transplantation is to expand the source of kidney, a large number of treatment of uremic patients a better way.