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妊娠期肝炎的严重性和发生率都呈现很大的地区性变化。在美国(Zonde KandBromberg 1974;Serer and White1968)和西欧大约有一或二万分之一的孕妇合并肝炎,但在印度约为0.5%(Mal-kani and Grewel 1675;Naidu andVsswanathan,1975),非洲(Morrowet al,1968)和中东则较为普遍。有个惊奇的发现,在这些高度流行地区的妇女,其幼年时代避免了感染,而在其成年的生活中仍易感。是否由于在不同的国家乙型肝炎病例的比例不同,而是不知道的,在英国和美国约有20%的病例为 HBsAg 阳性(Keys et al 1972;Cossart
Severe hepatitis and pregnancy rates have shown a great regional change. In pregnant women in the United States (Zonde KandBromberg 1974; Serer and White 1968) and Western Europe about one in 10,000 or in 10,000 are associated with hepatitis, but in India about 0.5% (Mal-kani and Grewel 1675; Naidu and Vswanathan 1975) al, 1968) and the Middle East are more common. It has been astonishing to find that women in these highly endemic areas, who were infected at an early age, are still susceptible to their adult lives. Whether or not the proportion of hepatitis B cases is different in different countries is unknown, and about 20% of cases in the United Kingdom and the United States are HBsAg positive (Keys et al 1972; Cossart