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报告1例儿童寻常性银屑病并发继发性血小板增多症。患儿男,7岁。躯干及四肢散在分布红斑、鳞屑1个月,血常规示血小板1654×109/L。皮肤科检查:躯干及四肢散在分布黄豆至硬币大炎性红斑,表面附着银白色鳞屑,刮除后可见薄膜现象和Auspitz征阳性。皮损组织病理检查:表皮角化不全,角质层可见Munro微脓肿,颗粒层变薄,部分消失,棘层肥厚,部分呈棒槌状伸入真皮;真皮浅层毛细血管扩张及炎性细胞浸润。诊断:寻常性银屑病并发继发性血小板增多症。予口服消银颗粒,外用地奈德乳膏及卡泊三醇软膏治疗后皮损消退,血小板下降明显。
Report of 1 case of children with psoriasis complicated by secondary thrombocythemia. Children male, 7 years old. Scattered distribution of the trunk and limbs erythema, scaly 1 month, blood platelets showed 1654 × 109 / L. Dermatology examination: the trunk and limbs scattered in the distribution of soybeans to the coin large inflammatory erythema, the surface attached to the silver-white scales, after curettage and the Auspitz sign positive. Skin lesions histological examination: epidermal keratosis, the Munro micro abscess can be seen in the stratum corneum, thinning of the granular layer, partially disappeared, acanthosis hypertrophy, part of the clubroom into the dermis; superficial telangiectasias and inflammatory cell infiltration. Diagnosis: Psoriasis vulgaris complicated with secondary thrombocythemia. To oral silver particles, external use of Nedal cream and calcipotriol ointment subsided after treatment, platelet decreased significantly.