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为了降低新生儿高未结合胆红素血症 (简称高胆 )的病死率和伤残率 ,选择 5 4例在新生儿期曾患高胆的病儿作 (甲组 ) ,并选正常儿童 30例作对照 (乙组 ) ,进行下列检查 :(1 )体格发育及神经系统检查 ;(2 ) 0～ 3岁用中国儿童发展中心儿童心理分中心编制小儿智能发育量表 (CDCC) ,4岁以上采用韦氏量表。结果显示 :1 .体格发育 :两组身长、体重、头围 P均 >0 .0 5。 2 .两组智能发育及运动发育各为6 5 .1 85 2± 2 9.90 0 8、90 .4± 1 2 .2 2 46分及 6 6 .30 77± 2 3.1 95 3、92 .3± 1 1 .7393分 ,t值各为 5 .5 36 3、5 .6 5 87P均 <0 .0 1。甲组患儿的智能与运动发育明显低于乙组。 3.5 4例中原有胆红素脑病 1 0例。随访时发现脑瘫 2 4例 ,(44 .4% ) ,先天愚型 1例。结论 :1 .普及对高胆的知识 ,正确干预。 2 .提出胆红素脑病的早期表现。 3.做好早期诊断脑瘫。 4.做好高胆脑病的防治
In order to reduce the mortality and morbidity of neonatal unconjugated hyperbilirubinemia (54 cases), 54 cases of children with high bile in neonatal period were selected as group A (Group A), and normal children 30 cases of control group (B), the following checks: (1) physical development and neurological examination; (2) 0 to 3 years old with children’s psychological center of China Children’s Development Center for the preparation of children’s mental development scale (CDCC), 4 Wechsler scale above the age of. The results showed that: 1. Physical development: body length, weight, head circumference P were> 0.05. 2, the two groups of intelligent development and sports development were 6 5 .1 85 2 ± 2 9.90 0 8,90 .4 ± 1 2 .2 2 46 points and 6 6 .30 77 ± 2 3.1 95 3,92 .3 ± 1 1 .7393 points, t values of 5 .5 36 3,5 .6 5 87P are <0. Group A children’s intelligence and exercise development was significantly lower than the B group. 3.5 4 cases of central bilirubin encephalopathy 10 cases. During the follow-up, 24 cases of cerebral palsy were found (44.4%) and one case of Down’s syndrome. Conclusion: 1. Popularize the knowledge of high bile, correct intervention. Put forward the early manifestation of bilirubin encephalopathy. 3. Good early diagnosis of cerebral palsy. 4. Do a good job in the prevention and treatment of biliary encephalopathy