类风湿因子(RF)与免疫复合物(IC)有着不可分割的密切关系。IgG类抗体与相应抗原结合形成IC后,就可获得对RF的极强反应性,这点可在类风湿性关节炎(RA)患者的关节液中检测到变性IgGRF与IC结合而形成大分子复合物的事实得以证明,RF主要是IgM类抗体(IgM—RF)。一部分为IgG类抗体(IgG—RF),它们相互结合后即可形成具有强烈活性的中等大小 Rheumatoid factor (RF) and immune complexes (IC) are inextricably linked. IgG class antibodies and the corresponding antigen to form IC, you can get a very strong RF response, which can be detected in rheumatoid arthritis (RA) patients with joint fluid degeneration IgGRF and IC to form a large molecule The fact that the complex has been demonstrated, RF is mainly IgM-like antibody (IgM-RF). Part of the IgG class antibodies (IgG-RF), they combined with each other to form a strong activity of medium size