本文探讨如何应用抗菌药防止尿路感染的反复发作。 60例女性患者,均有尿路感染反复发作的历史,并在过去1年内最少曾有2次以上的发作并经尿细菌定量培养证实。致病菌多为大肠杆菌。其中45例患者随机分为3组:①磺胺甲基异(口恶)唑200mg+甲氧苄氨嘧啶40mg;②呋喃坦啶100mg;③安慰剂(对照组);其余15例因对磺胺或呋喃坦啶过敏,单用甲氧苄氨嘧啶0.1g。上述各组均每日服药1次,用药半 This article explores how to use antimicrobial agents to prevent recurrent urinary tract infections. All 60 female patients had a history of recurrent urinary tract infections and had had at least 2 episodes in the past year and were confirmed by quantitative culture of urinary bacteria. Pathogenic bacteria mostly E. coli. 45 patients were randomly divided into three groups: ① sulfamethoxazole 200mg + trimethoprim 40mg; ② furadanthin 100mg; ③ placebo (control group); the remaining 15 cases due to sulfa or furan Tanelline allergy, trimethoprim alone 0.1g. The above groups were daily medication 1, medication half