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目的研究广东省江门地区布鲁菌病的发病特点、规律、临床诊断及治疗特点。方法对广东省江门市中心医院2009年1月至2013年7月收治的21例布鲁菌病患者的流行病学资料、临床表现、实验室检查、治疗和转归等情况进行回顾性分析。结果 21例患者均为本地区居民,在本地发病,6例为猪饲养职业人员,4例吃过烤羊肉串,2例吃过羊杂,其余9例传染途径不明确。21例患者均有发热,以中度热及高热为主,初诊均误诊,后经血培养检出布鲁菌阳性确诊,给予利福平、多西环素、左氧氟沙星等联合治疗,21例患者全部治愈,随访3个月正常。结论布鲁菌病在江门市除2001年外来1例,多年未见报道,且因临床表现不典型,极易误诊或漏诊,临床医生应拓宽思路,对长期发热、经常用抗生素治疗无效的患者,要警惕,注意此病的鉴别诊断,血培养是简单、有效的诊断方法,选择敏感抗生素治疗有效,一般预后良好。
Objective To study the characteristics, regularity, clinical diagnosis and treatment of brucellosis in Jiangmen, Guangdong Province. Methods The epidemiological data, clinical manifestations, laboratory tests, treatment and prognosis of 21 cases of brucellosis admitted to Central Hospital of Jiangmen City from January 2009 to July 2013 were retrospectively analyzed. Results All the 21 patients were residents in this area. The incidence was local, 6 were hogs, 4 were eared shish kebabs, 2 were eweed, and the remaining 9 were not clearly identified. Twenty-one patients had fever, with moderate and high fever, and newly diagnosed patients were all misdiagnosed. Brucella was confirmed by blood culture, and combined treatment with rifampin, doxycycline and levofloxacin, all of 21 patients Cured, followed up for 3 months normal. Conclusion Brucellosis in Jiangmen City in 2001 except 1 cases of foreign, has not been reported for many years, and because of clinical manifestations of atypical, easily misdiagnosed or missed diagnosis, clinicians should broaden their thinking, long-term fever, often with antibiotic treatment ineffective patients , To be alert, pay attention to the differential diagnosis of the disease, blood culture is a simple and effective diagnostic method, the choice of effective antibiotic treatment, the general prognosis is good.