降钙素基因相关肽 (CGRP)广泛分布于中枢和外周神经系统以及某些器官组织中 ,是由辣椒素敏感的感觉神经末梢释放的肽类物质。有强烈舒张血管、降血压、激动心肌、正性变时变力、抑制血管平滑肌增殖、血小板聚集、免疫调节等作用。与心血管疾病相关 ,特别是与高血压密切相关。参与高血压的发生和发展 ,可以作为抗高血压的物质 ,故近十几年来CGRP与高血压关系的研究十分活跃 Calcitonin gene-related peptide (CGRP) is widely distributed in the central and peripheral nervous system and some organs and tissues, and is a peptide released from capsaicin sensory nerve endings. A strong relaxation of blood vessels, lowering blood pressure, cardiac muscle, positive variable time-varying, inhibition of vascular smooth muscle proliferation, platelet aggregation, immune regulation and so on. And cardiovascular disease, especially with high blood pressure are closely related. Involved in the occurrence and development of hypertension can be used as antihypertensive substances, so the past decade the relationship between CGRP and hypertension is very active