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目的:探讨年龄和性别与冠状动脉病变严重程度的相关性。方法:452例行冠状动脉造影住院患者据造影结果分为冠心病组(n=328)和对照组(n=124),以性别、年龄、高血压病、糖尿病、血脂、载脂蛋白等多重危险因素及冠脉评分进行多变量分析。结果:冠心病组男性比例、年龄均高于对照组(P<0.01);多元logistic回归分析显示:年龄、性别、高血压病和糖尿病与冠心病独立相关(P<0.05);逐步回归分析结果显示:年龄、性别、载脂蛋白B、高血压病与冠脉病变评分独立相关(P<0.01)。结论:年龄和性别与冠状动脉病变严重程度密切相关。
Objective: To investigate the relationship between age and gender and the severity of coronary artery disease. Methods: 452 patients undergoing coronary angiography were divided into coronary heart disease group (n = 328) and control group (n = 124) according to the angiographic results. The patients were divided into two groups according to gender, age, hypertension, diabetes mellitus, Multivariate analysis of risk factors and coronary artery scores. Results: The male ratio and the age in CHD group were higher than those in control group (P <0.01). Multivariate logistic regression analysis showed that age, gender, hypertension and diabetes were independently associated with coronary heart disease (P <0.05) The results showed that age, sex, apolipoprotein B and hypertension were independently associated with coronary artery disease scores (P <0.01). Conclusion: Age and sex are closely related to the severity of coronary artery disease.