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目的：对膀胱癌患者在施行膀胱肿瘤切除术后，采用顺铂作膀胱粘膜下注射的方法，以预防膀胱癌术后复发。方法：治疗组３４例，在距肿瘤２ｃｍ的正常粘膜处切除肿瘤后，以顺铂４０ｍｇ稀释后，作膀胱粘膜下注射；对照组３０例，仅作膀胱肿瘤切除；术后两组均常规采用顺铂膀胱灌注，并随访复发情况。对复发率的比较采用χ２检验。结果：两组经１～６年随访，治疗组复发３例，复发率８．８％；对照组复发９例，复发率３０．０％；两组差异有显著性（χ２＝４．６９，Ｐ＜０．０５）。结论：膀胱肿瘤切除加术中膀胱粘膜下注射顺铂的方法，可明显降低膀胱癌术后的复发率。
Objective: To treat bladder cancer patients after bladder tumor resection, the use of cisplatin bladder submucosal injection method to prevent postoperative recurrence of bladder cancer. Methods: The treatment group of 34 cases, 2cm away from the tumor after the tumor at the normal mucosa, with cisplatin 40mg diluted for submucosal bladder injection; control group of 30 cases, only for bladder tumor resection; after both groups were routinely used Cisplatin bladder perfusion, and follow-up relapse. The recurrence rate comparison using χ2 test. Results: After 1 to 6 years of follow-up, the recurrence rate was 8.8% in the treatment group and 9% in the control group, with a recurrence rate of 30.0%. There was significant difference between the two groups (χ2 = 4.69, P <0.05). Conclusion: Bladder tumor resection plus intraoperative submucosal instillation of cisplatin can significantly reduce the recurrence rate of bladder cancer.