作者用不同浓度的咪喹莫特(imiquimod)霜和空白霜剂治疗了311例<男180例,女131例)肛门生殖器疣患者,并对咪喹莫特的疗效和安全性进行了评价。 方法:将按标准入选的311例尖锐湿疣患者随机分成3组,分别予5％及1％咪喹莫特霜和空白霜剂自行外用。具体方法是:晚上用药一次,每周3次,共16周或至疣体全部脱落为止。结果:疣清除率:在原计划入选用药16周 The authors treated 311 patients (180 males and 131 females) with genital warts at different concentrations of imiquimod cream and blank cream and evaluated the efficacy and safety of imiquimod. METHODS: A total of 311 patients with condylomata acuminatum who were selected according to the criteria were randomly assigned to three groups, topically treated with 5% and 1% imiquimod cream and blank cream respectively. The specific method is: medication once at night, three times a week for a total of 16 weeks or until the wart all fall off. Results: Warts clearance rate: in the original planned drug selection for 16 weeks