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目的 :评价脉络宁注射液预防急性缺血性心脑血管疾病的效果。方法 :符合条件者 4 92例 ,分脉络宁治疗组 ,用脉络宁 30ml静滴 ,qd ,15天为一个疗程 ;对照组 ,用蝮蛇抗栓酶 0 75u静滴 ,疗程用法相同。每年 4月和10月份各治疗 1个疗程。所有病人连续治疗并随访 3年 ,观察有无急性缺血性心脑血管病事件。结果 :脉络宁治疗组发生急性缺血性心脑血管病事件 8例 ,发生率为 3 2 % ,未发现严重不良反应 ;对照组急性缺血性心脑血管病事件发生率为 2 9% ,但 3例出现严重不良反应。结论 :脉络宁可有效降低急性缺血性心脑血管病事件的发生率 ,不良反应少
Objective: To evaluate the effect of Mailuoning injection in preventing acute ischemic cardiovascular and cerebrovascular diseases. Methods: In line with the conditions of 4 92 cases, Fen Mailu treatment group, with Mailuoning 30ml intravenous infusion, qd, 15 days for a course of treatment; control group, with viper antithrombin 075u intravenous infusion, the same course of treatment. April and October each treatment of a course of treatment. All patients were treated and followed up for 3 years to observe the occurrence of acute ischemic cardiovascular and cerebrovascular diseases. Results: There were 8 cases of acute ischemic cardiovascular and cerebrovascular disease in Mailuoning treatment group, the incidence rate was 32%, no serious adverse reaction was found. The incidence of acute ischemic cardiovascular and cerebrovascular disease in control group was 29% However, 3 patients developed serious adverse reactions. Conclusion: Mailuoning can effectively reduce the incidence of acute ischemic cardiovascular and cerebrovascular events, fewer adverse reactions