患者女性，40岁。住院号205315。因浮肿，少尿1周入院。查体：脉搏67次/分，血压22/12kPa，眼睑及面部轻度浮肿，心肺（－），左肾区叩击痛（+），双下肢Ⅱ·凹陷性水肿。原蛋白定性（+++），红细胞少许。似诊：急性肾小球肾炎。入院后给予青霉素640万~u加入生理盐水200毫升中静脉滴注，每日一次。治疗第三天，患者在静脉滴青霉素时产生迟发型过敏反应，应用抗组织胺药物及对症处理后症状缓解。次日换用头孢拉定（上海施贵宝制药有限公司生产）4克加入生理盐水25毫升中静滴，于30分钟时患者面色苍白，感胸闷，心 Female patient, 40 years old. Hospital number 205315. Due to edema, oliguria 1 week admission. Examination: pulse 67 beats / min, blood pressure 22 / 12kPa, edema and facial mild edema, cardiorespiratory (-), left renal percussion pain (+), lower extremity Ⅱ · depression edema. Qualitative protein (+++), a little red blood cells. As a diagnosis: acute glomerulonephritis. After admission to penicillin 6.4 million ~ u added 200 ml of normal saline intravenously, once daily. The third day of treatment, patients with intravenous penicillin produce delayed-type allergic reactions, the application of anti-histamine drugs and symptomatic treatment of symptoms. The next day for Cefradine (Shanghai Squibb Pharmaceutical Co., Ltd.) 4 g added 25 ml of normal saline intravenously, at 30 minutes the patient pale, chest tightness, heart