康妇消炎栓联合莫西沙星治疗慢性盆腔炎的临床效果观察

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目的 观察康妇消炎栓联合莫西沙星治疗慢性盆腔炎的临床效果.方法 选取丽水市妇幼保健院2016年11月至2018年11月收治的慢性盆腔炎患者216例,按照随机数字分组法分为对照组与观察组,每组108例.对照组患者给予盐酸莫西沙星片治疗,观察组患者给予康妇消炎栓联合盐酸莫西沙星片治疗.比较治疗后两组患者相关临床体征消失时间、临床治疗效果及不良反应发生情况.结果 观察组患者发热[(5.15±2.46)h]、下腹疼痛[(7.62±2.77)h]、白带异常[(9.16±3.13)h]、腹部坠胀[(6.38±2.03)h]等盆腔炎相关临床症状消失时间均显著短于对照组发热[(8.09±2.28)h]、下腹疼痛[(10.45±2.68)h]、白带异常[(12.20±2.96)h]、腹部坠胀[(9.49±2.27)h]等消失时间,均差异有统计学意义(t=8.231、7.631、7.334、10.613,均P=0.000);观察组患者治疗总有效率(93.51%)显著高于对照组(86.11%),差异有统计学意义(χ2=6.983,P=0.008);观察组患者不良反应总发生率(3.70%)显著低于对照组(11.11%),差异有统计学意义(χ2=4.320,P=0.038).结论 相对于单纯使用喹诺酮类抗菌药莫西沙星,采用康妇消炎栓联合莫西沙星治疗慢性盆腔炎有更为良好的临床治疗效果及更低的不良反应发生率.“,”Objective To explore theclinical effect of Kangfu Xiaoyansuppositorycombined with moxifloxacin in the treatment of chronic pelvic inflammatory disease.Methods From November 2016 to November 2018,a total of 216 patients with chronic pelvic inflammatory disease admitted to the Maternal and Child Health Care Hospital of Lishui were enrolled .The patients were divided into control group and observation group according to the digital table , with 108 cases in each group .The patients in the control group were treated with quinolone antibacterial agent moxifloxacin hydrochloride tablets .The patients in the observation group were treated with Kangfu Xiaoyan suppository and moxifloxacin hydrochloride tablets .The disappearance time of clinical signs ,clinical treatment effects and adverse reactions in the two groups after treatment were observed and compared .Results The disappearance time of fever [(5.15 ±2.46)h],lower abdominal pain[(7.62 ±2.77)h],leucorrhea abnormality[(9.16 ±3.13)h],and pain [(6.38 ±2.03) h] in the observation group were significantly shorter than those in the control group [(8.09 ± 2.28)h,(10.45 ±2.68)h,(12.20 ±2.96)h,(9.49 ±2.27)h](t=8.231,7.631,7.334,10.613,all P=0.000). The total effective rate of the observation group (93.51%) was significantly higher than that of the control group (86.11%),the difference was statistically significant (χ2 =6.983,P=0.008).The overall incidence of adverse reactions of the observation group (3.70%) was significantly lower than that of the control group (11.11%),and the difference was statistically significant (χ2 =4.32,P =0.038).Conclusion Compared with the simple use of moxifloxacin ,Kangfu Xiaoyan suppository combined with moxifloxacin in the treatment of gynecological chronic pelvic inflammatory disease has a better clinical treatment effect and a lower incidence of adverse reactions .It is recommended to apply in clinical treatment in the future .
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