新生儿黄疸是新生儿时期常见症状之一,尤其是早期新生儿,约60%~85%的新生儿会出现黄疸[1]。黄疸是由体内胆红素浓度升高引起,当血液中未结合胆红素浓度过高时,可以通过血-脑脊液屏障(简称“血脑屏障”),引起急性神经功能障碍和慢性神经系统损伤,分别称为急性胆红素脑病和核黄疸。大多数学者关注于胆红素对脑组织的损害,胆 Neonatal jaundice is one of the common symptoms in neonatal period, especially in early neonates. About 60% to 85% of newborns will develop jaundice [1]. Jaundice is caused by the elevated bilirubin concentration in the body, which can cause acute neurological dysfunction and chronic through the blood-cerebrospinal fluid barrier (“BBB” for short) when the level of unconjugated bilirubin in the blood is too high Nervous system damage, respectively, called acute bilirubin encephalopathy and nuclear jaundice. Most scholars focus on bilirubin damage to brain tissue, gallbladder