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目的了解广州市2002-2013年报告的艾滋病病毒(HIV)抗体阳性孕产妇的疫情,以及母婴传播干预情况。方法运用趋势卡方分析,对2002-2013年报告的HIV抗体阳性孕产妇病例的晚发现、接受母婴阻断干预与随访等情况进行分析。结果 2002-2013年,广州市累计报告HIV抗体阳性孕产妇278例,现存活261例。其中常住病例占64.4%(168例),平均年龄为27.6岁,异性传播占85.4%(223例),HIV感染者占70.1%(183例),AIDS病例所占比例呈下降的趋势(趋势χ2=8.46,P=0.004);接受HIV母婴阻断干预措施的病例占66.5%;常住病例中选择继续妊娠者所占比例(51.8%)高于非常住病例(38.7%)(χ2=4.556,P=0.033);已分娩婴儿中失访比例为41.4%。结论应加强孕产妇人群及其配偶的HIV抗体检测工作,孕产妇病例分娩婴儿的随访监测工作,是母婴传播干预工作的重点。
Objective To understand the epidemic situation of HIV-positive pregnant women reported in Guangzhou from 2002 to 2013 and the intervention of mother-to-child transmission. Methods The trend chi-square analysis was used to analyze the late detection of HIV antibody positive maternal cases reported in 2002-2013 and the intervention and follow-up of maternal and child block. Results From 2002 to 2013, a total of 278 HIV-positive pregnant women were reported in Guangzhou, and 261 were alive. Among them, 64.4% (168 cases) were resident, with an average age of 27.6 years, with heterosexual transmission accounting for 85.4% (223 cases) and HIV-infected persons accounting for 70.1% (183 cases). The proportion of AIDS cases showed a decreasing trend (trend χ2 = 8.46, P = 0.004). 66.5% of the interventions received interventions for preventing mother-to-child HIV. The proportion of those who chose to continue with pregnancy was higher than that of non-resident patients (38.7%) (χ2 = 4.556, P = 0.033). The proportion of lost babies who had given birth was 41.4%. Conclusion HIV antibody testing of pregnant women and their spouses should be strengthened and follow-up monitoring of babies born in maternal cases should be the focus of mother-to-child transmission intervention.