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作者过去已有初步报告证实高脂蛋白血症Ⅳ型(高前-β-脂蛋白血症)与胆囊疾病(GBD,即胆石症、胆囊炎、胆囊切除术)的发病率异常增高有关,而在高脂蛋白血症Ⅱa型(高-β-脂蛋白血症),GBD发病率仍属正常。本文报告在210例高脂血症患者,包括一组Ⅱb型高脂血症(高-β-和高前-β-脂蛋白血症结合)患者中的发现。结果各组患者平均年龄51～57岁。在每型高脂蛋白血症中,有一个趋势,即GBD患者体重比无GBD的患者高一些。Ⅱb型和Ⅳ型脂蛋白血症患者体重比Ⅱa型高脂蛋白血症患者重一些。Ⅱa、Ⅱb和Ⅳ型高脂蛋白血症的女性GBD的总发病率分别为
The authors have previously reported that hyperlipoproteinemia type IV (pre-pro-β-lipoproteinemia) has been associated with an abnormally high incidence of gallbladder disease (GBD), namely cholelithiasis, cholecystitis, cholecystectomy In hyperlipoproteinemia type IIa (hyper-beta-lipoproteinemia), the incidence of GBD remains normal. This paper reports findings in 210 patients with hyperlipidemia, including a group of patients with type IIb hyperlipidemia (combination of high-β and high pre-β-lipoproteinemia). Results The average age of patients in each group 51 to 57 years old. In each type of hyperlipoproteinemia, there is a tendency that GBD patients have a higher body weight than those without GBD. Patients with type IIb and type IV lipoproteinemia weigh heavier than those with type IIa hyperlipoproteinemia. The overall incidence of female GBD for type IIa, IIb and type IV hyperlipoproteinemia was