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最近,由Naman等从SV-40转化骨髓细胞系分泌物中提纯一种25KDa蛋白,并建立了它的cDNA克隆,天然的和重组的分子均促进骨髓B 细胞系增殖,且与已知的白细胞介素(IL-1～IL-6)都不同,故被称为IL-7。至于以前一些研究小组描述的由骨髓基质细胞分泌的有B 细胞生长活性的因子是否与IL-7相同有待证明。本文作者研究了rIL-7对一些细胞增殖和分化作用,这些细胞均为建系细胞包括骨髓前B 细胞克隆
Recently, a 25 kDa protein was purified from SV-40 transformed bone marrow cell line secretions by Naman et al. And its cDNA clone was established. Both native and recombinant molecules promote the proliferation of bone marrow B cell lines and are associated with known white blood cells Interleukin (IL-1 ~ IL-6) are different, it is called IL-7. As for some previous research team described by bone marrow stromal cell secretion of B cell growth factor whether IL-7 with the same factors to be proved. The authors investigated the effects of rIL-7 on the proliferation and differentiation of a number of cells, all of which are constitutively, including pre-B cell clone