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1973~1993年治疗霍奇金病212例,年龄21~40岁者占56%,女性占54%,均经淋巴结组织形态学检查确诊,结节硬化型占52%,Ⅰ~Ⅱ_A期病例进行放射治疗,86.4%的病例存活7年以上无复发。 54.7%的病例发生Ⅰ~Ⅱ度放射性肺纤维化,Ⅲ度肺纤维化均有呼吸功能障碍,并且长期不能恢复。0.79%的病例发生放射性心包炎,心包炎的发生率较低与放疗时遮蔽左室2/3以及并用糖皮质激素有关。颈部
Between 1973 and 1993, 212 cases of Hodgkin’s disease were treated, accounting for 56% of patients aged 21 to 40 years and females 54%. All patients were diagnosed by histomorphological examination of lymph nodes. Nodules sclerosis accounted for 52%. Cases I to II_A were performed. In radiation therapy, 86.4% of patients survived for more than 7 years without recurrence. In 54.7% of cases, I-II radiation-induced pulmonary fibrosis occurred, and in III-degree pulmonary fibrosis, respiratory function was impaired and could not be recovered in the long term. Radioactive pericarditis occurred in 0.79% of cases. The lower incidence of pericarditis was related to occlusion of left ventricle 2/3 and concurrent use of corticosteroids during radiotherapy. neck