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目的:探讨自拟中药汤剂对小儿上呼吸道感染合并心肌损害的治疗作用及临床疗效。方法:将158例上呼吸道感染合并心肌损害的患儿随机分为治疗组和对照组。对照组只予西药常规治疗,治疗组在对照组的常规治疗基础上加用自拟中药汤剂口服,并于治疗前后做了血清心肌肌钙蛋白I(CTnI)、血清肌酸激酶(CK-MB)的检测。结果:治疗组、对照组治疗后临床症状及CK-MB的恢复均较治疗前明显减轻(P<0.01)。治疗组有效率78%,对照组有效率42%,有效率比较有非常显著性差异(P<0.001);治疗组与对照组治疗后比较,治疗组在CTnI、CK-MB的恢复上优于对照组(P<0.01)。结论:自拟中药汤剂对小儿上呼吸道感染合并心肌损害的患儿的CTnI和CK-MB恢复有显著疗效(P<0.01)。
Objective: To explore the curative effect and clinical efficacy of self-made traditional Chinese medicine decoction on children with upper respiratory tract infection combined with myocardial damage. Methods: 158 cases of upper respiratory tract infection with myocardial damage were randomly divided into treatment group and control group. The control group was treated with routine western medicine only. The treatment group was treated with traditional Chinese medicine decoction orally on the basis of routine treatment in the control group, and serum CTnI and CK- MB) detection. Results: After treatment, the clinical symptoms and the recovery of CK-MB in the treatment group and the control group were significantly relieved (P <0.01). The effective rate of the treatment group was 78%, while that of the control group was 42%, the effective rate was significantly different (P <0.001). The treatment group and the control group were better than the control group in the recovery of CTnI and CK-MB Control group (P <0.01). Conclusion: The curative effect of self-made Chinese medicine decoction on the recovery of CTnI and CK-MB in children with upper respiratory tract infection complicated with myocardial damage was significant (P <0.01).