2014年1月8日,美国食品和药品管理局(FDA)发出警告~([1]):超剂量应用非处方药磷酸钠治疗便秘,可引起罕见、严重的肾脏和心脏损害,甚至导致死亡。磷酸钠用于缓解偶发性便秘,剂型包括口服溶液和灌肠剂,推荐每日给药1次且用药不超过3 d。磷酸钠超剂量使用可引起严重脱水以及磷酸盐、钙、钠等电解质紊乱,对肾脏和心脏造成严重的不良影响,甚至导致死亡。严重损害多发 On January 8, 2014, the U.S. Food and Drug Administration (FDA) warned that the overdose of over-the-counter sodium phosphate treatment of constipation can cause rare and severe kidney and heart damage and even death. Sodium phosphate is used to relieve occasional constipation. Formulations include oral solutions and enemas. It is recommended to administer once daily and not more than 3 days. Overdosage of sodium phosphate can cause severe dehydration and electrolyte imbalance of phosphate, calcium, sodium and other serious adverse effects on the kidneys and heart, and even lead to death. Severe damage multiple