G-CSF是由骨髓基质细胞产生的一种糖蛋白单体,在抗感染中起着非特异性的免疫作用,当机体受到细菌感染或其毒素的刺激后,在3～6小时内G-CSF迅速上千倍增加,同时在感染控制后24～48小时内降至正常。支气管哮喘(哮喘)是气道慢性变态反应性炎症性疾病,但在急性发作的治疗过程中98％左右的患儿接受了抗生素治疗,为此,我们通过测定血清G-CSF的方法,来探讨哮喘发作与细菌感染的关系,为抗生素在哮喘的合理应用提供科学依据。 G-CSF is a glycoprotein monomer produced by bone marrow stromal cells and plays a nonspecific immune role in anti-infective. G-CSF, when stimulated by bacterial infection or its toxin, Quickly multiplied by a thousand times and also dropped to normal within 24-48 hours after infection control. Bronchial asthma (asthma) is a chronic allergic inflammatory disease of the airways, but about 98% of children undergoing an episode of acute exacerbation have been treated with antibiotics. To this end, we examined the method of serum G-CSF The relationship between asthma attack and bacterial infection provides a scientific basis for rational use of antibiotics in asthma.