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目的:观察镇痛泵用于重度子痫前期患者术后对防治产后子痫的效果。方法:将129例重度子痫前期剖宫产术后患者随机分为两组。治疗组术后于硬膜外导管处连接镇痛泵,实施连续硬膜外持续镇痛48 h;对照组术后采用双氯芬酸钠塞肛,注射盐酸哌替啶进行止痛。观察两组的术后镇痛效果、术后48 h血压变化情况和产后子痫发生率。结果:治疗组术后48 h内患者自述完全无痛或轻微疼痛能够忍受,对照组疼痛剧烈;治疗组术后48 h内血压基本平稳,对照组术后2 h后血压开始上升。两组比较收缩压与舒张压均差异有统计学意义(P<0.05),产后子痫发生率两组有显著性差异(P<0.01)。结论:重度子痫前期患者术后应用镇痛泵镇痛效果满意,并能够使血压降到理想水平,可有效防止术后产后子痫的发生。
Objective: To observe the effect of analgesia pump on prevention and treatment of postpartum eclampsia in patients with severe preeclampsia. Methods: 129 patients with severe preeclampsia after cesarean section were randomly divided into two groups. The patients in the treatment group were given analgesia pump at the epidural catheter and were given continuous epidural analgesia for 48 hours. The patients in the control group were treated with diclofenac sodium and the injection of pethidine hydrochloride for analgesia. Postoperative analgesia, postoperative blood pressure changes at 48 h and the incidence of postpartum eclampsia were observed. Results: The patients in the treatment group were able to tolerate painless or mild pain completely within 48 hours after operation. The pain intensity in the control group was severe. The blood pressure was stable within 48 hours after operation in the treatment group. The blood pressure began to rise in the control group 2 hours after the operation. The systolic blood pressure and diastolic blood pressure were significantly different between the two groups (P <0.05). The incidence of postpartum eclampsia was significantly different between the two groups (P <0.01). Conclusion: The application of analgesic pump in patients with severe preeclampsia has satisfactory analgesic effect, and the blood pressure can be reduced to the ideal level, which can effectively prevent post-natal eclampsia.