论文部分内容阅读
心肌梗塞后应用阿司匹林的作用尚待确定。一些研究认为,急性心肌梗塞(AMI)后1周内应用阿司匹林可提高患者生存率,但其作用机理尚未阐明。作者用随机、安慰剂对照法对首次前壁 AMI 患者进行早期应用小剂量阿司匹林(100mg/d)的前瞻性研究,旨在评价该药对缩小梗塞范围及改善临床情况的影响。病人和方法将症状出现<12h、心电图证实有首次前壁 AMI 征象、无应用阿司匹林禁忌症的患者列为研究对象。入院后12h 内,病人随机分组,每日
The role of aspirin after myocardial infarction remains to be determined. Some studies suggest that aspirin may improve survival in patients within 1 week after acute myocardial infarction (AMI), but its mechanism of action has not been elucidated. The authors randomized, placebo-controlled, first prospective AMI patients with a low-dose aspirin (100 mg / d) prospective study to assess the effect of the drug on narrowing infarct size and improving clinical outcomes. Patients and methods showed symptoms <12h, evidence of first AMI on the anterior wall by electrocardiogram, and no aspirin contraindications in patients as study subjects. Within 12 hours after admission, patients were randomized to receive daily doses