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氯苯乙烯与苯乙烯相比较,具有反应性高,不易燃、耐热、和不易爆等特点,已开始生产和使用。作者用小白鼠对苯乙烯和氯苯乙烯的急性毒性和残留性进行了比较实验。结果如下: 苯乙烯和氯苯乙烯的经口LD_(50)分别为1,470(1,270～1,690)和1,230(1,130～1,320)毫克/公斤;经腹腔LD_(50)分别为870(740～1,030)和1,090(980～1,220)毫克/公斤;急性吸入(每天5小时,吸入3天)LC_(50)分别为700和450ppm。腹腔给药后用气相色谱法定时测量体内残留量,苯乙烯和氯苯乙烯均与给药后
Chlorinated styrene and styrene compared with high reactivity, non-flammable, heat-resistant, and non-explosive characteristics have begun to produce and use. The authors compared the acute toxicity and residual properties of styrene and chlorostyrene in mice. The results were as follows: The LD50 of styrene and chlorostyrene were 1,470 (1,270-1,690) and 1,230 (1,130-1,320) mg / kg, respectively. The LD 50 of abdominal cavity were 870 (740-1,030) and 1,090 (980 to 1,220) mg / kg; acute inhalation (5 hours daily, inhalation for 3 days) with LC50 values of 700 and 450 ppm, respectively. After intraperitoneal administration, the residual amount in the body was measured by gas chromatography regularly. Both styrene and chlorostyrene