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目的:探讨音乐疗法联合亚高温热化疗治疗深部恶性肿瘤的疗效及机制。方法 80例晚期恶性肿瘤患者,随机分为观察组(40例)和对照组(40例),观察组患者音乐疗法联合亚高温热化疗治疗;对照组患者经单纯化疗治疗。结果两组治疗后临床症状改善KPS评分评价,治疗组优于对照组,差异有统计学意义(P<0.05);客观疗效评定差异无统计学意义(P>0.05),两组治疗前后免疫功能变化比较:。治疗后两组比较,观察组CD3+、CD4+、CD3+/CD8+及NK细胞较对照组升高(P<0.05)。结论音乐疗法联合亚高温热化疗治疗深部恶性肿瘤疗效较好,未见明显不良反应。
Objective: To explore the efficacy and mechanism of music therapy combined with hyperthermia hyperthermia in the treatment of deep malignant tumors. Methods Eighty patients with advanced malignant tumor were randomly divided into the observation group (40 cases) and the control group (40 cases). The patients in the observation group were treated with music therapy combined with hyperthermia and hyperthermia. The patients in the control group were treated with chemotherapy alone. Results After treatment, the clinical symptoms improved KPS score evaluation, the treatment group was superior to the control group, the difference was statistically significant (P <0.05); there was no significant difference in the objective curative effect assessment (P> 0.05) Change comparison:. After treatment, CD3 +, CD4 +, CD3 + / CD8 + and NK cells in observation group were higher than those in control group (P <0.05). Conclusion The combination of music therapy and hyperthermal hyperthermia in the treatment of deep malignant tumors has good curative effect and no obvious adverse reactions.