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本文对45例颅内乳头状肿瘤进行了病理分析,其中包括15例脉络丛乳头状瘤,15例乳头状室管膜瘤及15例转移性乳头状腺癌。其中39例经免疫组化检测 GFAP,S-100及 CEA。结果显示大多数肿瘤光镜下可以区分,只有少数病例要求增加免疫组化染色检测。脉络丛乳头状瘤 S-100 9/9阳性,而 GFAP、CEA 均阴性;乳头状室管膜瘤15/15 GFAP(+).14/15 S-100(+);14/15转移性乳头状腺癌 CEA(+)。使用癌胚肮原,而不用角蛋白来区分颅内乳头状肿瘤更有价值。
In this paper, 45 cases of intracranial papillary tumors were pathologically analyzed, including 15 cases of choroid plexus papilloma, 15 cases of papillary ependymoma and 15 cases of metastatic papillary adenocarcinoma. 39 cases were detected by immunohistochemistry GFAP, S-100 and CEA. The results show that most tumors can be distinguished by light microscope, only a few cases require increased immunohistochemical detection. Choroid plexus papilloma S-100 9/9 positive, and GFAP, CEA were negative; papillary ependymoma 15/15 GFAP (+). 14/15 S-100 (+); 14/15 metastatic nipple Adenocarcinoma CEA (+). It is more valuable to use carcinoembryonic antigen rather than keratin to differentiate intracranial papillary tumors.