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前列腺癌是男性泌尿系统常见的恶性肿瘤之一,近年来其发病率在我国呈上升趋势。前列腺癌的最常用检测标志物就是前列腺特异性抗原(PSA),随着人们对PSA的不断认识,逐渐发现PSA的组织特异性较高,而癌特异性较差,其临床应用价值也有待重新评估,因此大量研究转向寻找新的前列腺癌标志物,目前已取得不少成果。本文从DNA、RNA和蛋白质水平三方面阐述前列腺癌标志物的研究进展,以期为前列腺癌的诊断和治疗提供新途径。
Prostate cancer is one of the common malignant tumors in male urinary system, and its incidence has been on the rise in our country in recent years. Prostate cancer is the most commonly used detection marker is prostate specific antigen (PSA), PSA PSA as people continue to recognize, and gradually found that tissue specificity of PSA is higher, and poor specificity of cancer, its clinical value has yet to be re- Assessment, so a lot of research turned to find new markers of prostate cancer, has achieved a lot of results. This article describes the progress of prostate cancer markers from three aspects of DNA, RNA and protein levels, in order to provide a new way for the diagnosis and treatment of prostate cancer.