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的 :总结近五年来卡他莫拉氏菌下呼吸道感染的临床特点及对抗生素的敏感性。方法 :(1 )分析 58例卡他莫拉氏菌所致肺部感染的临床资料 ,包括年龄、基础疾病、发病诱因、症状体征、X线表现、治疗转归等 ;(2 )以K -B法 (纸片法 )或Etest法 (MIC纸片法 )测定该菌的体外药敏性。结果 :(1 )男 44例 ,女 1 4例 ,年龄 54± 1 5岁 ,78%的患者有基础疾病 ,主要为COPD、肺心病。症状为咳嗽 (93 % )、发热 (60 % ) ,胸部X线表现为肺部斑片状阴影 (41 4% )。 (2 )药敏试验示该菌呈多重耐药 ,妥布霉素、氧氟沙星、头孢哌酮、头孢三嗪为较敏感抗生素。结论 :卡他莫拉氏菌下呼吸道感染患者多有基础疾病 ,临床表现不典型 ,诊断依靠病原学并结合临床及X线检查 ,治疗应根据药敏并联合应用抗生素
: To summarize the clinical characteristics of Moraxella catarrhal lower respiratory tract infection in recent five years and its sensitivity to antibiotics. Methods: (1) To analyze the clinical data of 58 cases of Moraxella catarrhali infection including age, basic disease, B method (paper method) or Etest method (MIC paper method) to determine the in vitro susceptibility of the bacteria. Results: (1) There were 44 males and 14 females, aged 54 ± 15 years and 78% of the patients had underlying diseases, mainly COPD and pulmonary heart disease. The symptoms were cough (93%), fever (60%), and chest radiographs of patchy shadows of the lungs (41.4%). (2) Susceptibility test showed that the bacteria was multi-drug resistance, tobramycin, ofloxacin, cefoperazone, ceftriaxone as more sensitive antibiotics. Conclusion: Moraxella catarrhal lower respiratory tract infection in patients with more underlying diseases, clinical manifestations are not typical, the diagnosis depends on etiology and clinical and X-ray examination, the treatment should be based on drug sensitivity combined with antibiotics