苄基β-氯乙基硫醚、苯基β-溴乙基硫醚、苄基β-氯乙基砜、苯基β-溴乙基砜分别与各种仲胺作用,制成一系列氨基上有各种不同取代基的β-氨基硫醚及β-氨基砜.有的β-氨基砜则由相应硫醚以过氧化氢氧化制成. 二苯甲磺酰乙酸与苯甲醛及醋酸铵共热,除获得预期产物二苯甲基β-氨基-β-苯基乙基砜外,并得副产品二苯甲基β-苯乙烯基砜及二苯甲基甲基砜.苄磺酰乙酸反应时也生成类似产物.二苯甲硫醇与甲醛及仲胺进行Mannich反应,生成预期的氨甲基化产物. Benzyl β-chloroethyl sulfide, phenyl β-bromoethyl sulfide, benzyl β-chloroethyl sulfone, phenyl β-bromoethyl sulfone, respectively, with a variety of secondary amine to make a series of amino There are a variety of different substituents of β-amino-sulfide and β-amino-sulfone.Some β-amino-sulfone by the corresponding thioether oxidation with hydrogen peroxide.Phenylbenzenesulfonyl acetic acid and benzaldehyde and ammonium acetate In addition to the expected product benzhydryl β-amino-β-phenylethyl sulfone, and by-products of benzhydryl β-styryl sulfone and benzhydryl methyl sulfone. A similar product is also produced during the reaction.Mannich reaction of diphenylmethanethiol with formaldehyde and secondary amine gives the expected aminomethylated product.