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目的观察综合康复理疗配合来氟米特治疗类风湿性关节炎(RA)的疗效及安全性。方法将80例RA患者随机分为两组,对照组患者给予来氟米特口服及对症治疗,治疗组在对照组治疗的基础上应用综合康复理疗。两组疗程均为3个月。结果治疗组总有效率显著高于对照组,差异有统计学意义(P<0.05);在关节疼痛数、关节压痛积分、关节肿胀积分、晨僵时间及20 m步行时间等方面,治疗组与对照组比较差异有统计学意义(P<0.05或P<0.01);两组均无严重不良反应发生。结论综合康复理疗配合来氟米特治疗RA疗效优于单用来氟米特,且安全性好。
Objective To observe the curative effect and safety of comprehensive rehabilitation therapy combined with leflunomide in the treatment of rheumatoid arthritis (RA). Methods Eighty RA patients were randomly divided into two groups. Patients in the control group received leflunomide oral and symptomatic treatment. The treatment group received comprehensive rehabilitation therapy based on the control group. Two groups of treatment are 3 months. Results The total effective rate in the treatment group was significantly higher than that in the control group (P <0.05). In the treatment group and the control group, the total effective rate was significantly higher in the treatment group than in the control group (P <0.05) The difference between the control group was statistically significant (P <0.05 or P <0.01); no serious adverse reactions occurred in both groups. Conclusion Comprehensive rehabilitation therapy combined with leflunomide in the treatment of RA is superior to leflunomide alone and has good safety.