论文部分内容阅读
现在主要采用手术和放疗相结合治疗颌面部恶性肿瘤,并在切除肿瘤的同时或延期施行整复手术以消除颌面部畸形。有报道这种整复手术的化脓感染并发症高达51.5%。已注意到放疗对手术区组织特别是对微循环床的不利影响,但是对恶性肿瘤患者放疗和手术后免疫指标的变化研究不够。为预防整复手术的并发症,作者研究免疫指标的变化,论证施行免疫矫正疗法的合理性。患者和方法检查施行整复手术的颌面部鳞癌(T_(2-4)N_(2-3)M_0)55例,男47例,女8例.平均年龄65.5岁。分两组,第1组20例,手术前未做特殊治疗。第2组15侧,术前远距γ线疗法总局灶刘量56Gy～65Gy。
Now the main combination of surgery and radiotherapy for the treatment of maxillofacial malignancies, and resection of the tumor at the same time or delay in the implementation of reconstructive surgery to eliminate maxillofacial deformity. It has been reported that such reconstructive surgery has a complication rate of up to 51.5%. Attention has been paid to the adverse effects of radiotherapy on the operation of the surgical area, especially on the microcirculation bed, but insufficient studies have been made on the changes of the immune indexes after radiotherapy and surgery in patients with malignant tumors. In order to prevent the complications of reconstructive surgery, the author studied the changes of immune indexes and demonstrated the rationality of immunomodulatory therapy. Patients and Methods 55 cases of maxillofacial squamous cell carcinoma (T_ (2-4) N_ (2-3) M_0), including 47 males and 8 females, with a mean age of 65.5 years. Divided into two groups, the first group of 20 cases, no special treatment before surgery. On the 15th side in Group 2, the total amount of Liu in the range of 56 Gy ~ 65 Gy from the distal gamma ray before operation.