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目的探索研究多索茶碱和氨茶碱治疗小儿重度支气管哮喘的临床疗效。方法随机抽取2012年12月~2013年12月本院接诊的62例小儿重度支气管哮喘作为研究对象,将其随机分为观察组和对照组,每组31例,对观察组患者采用多索茶碱进行治疗,对照组患者采用氨茶碱进行治疗,3天后比较两组患者的疗效和不良反应率。结果观察组总有效率100%显著高于对照组83.9%,二者比较差异显著(P<0.05);观察组并发症的发生率16.1%显著优于61.3%,二者差异显著(P<0.05)。结论多索茶碱用于治疗小儿重度支气管哮喘疗效显著,不良反应少,值得临床应用。
Objective To explore the clinical efficacy of doxofylline and aminophylline in the treatment of pediatric severe bronchial asthma. Methods 62 cases of pediatric severe bronchial asthma admitted to our hospital from December 2012 to December 2013 were randomly divided into observation group and control group with 31 cases in each group. Theophylline was treated with aminophylline in the control group, and the efficacy and adverse reaction rates were compared between the two groups after 3 days. Results The total effective rate in observation group was significantly higher than that in control group (100%, 83.9%, P <0.05). The incidence of complications in observation group was significantly better than that of 61.3% (P <0.05) ). Conclusion Doxofylline is effective in treating pediatric severe bronchial asthma with less adverse reactions and is worthy of clinical application.