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据国际医学年鉴统计,由遗传和内分泌导致的矮身材发病率为43人/万。目前我国有此类患者已达数百万之多,显然对提高民族生理素质是一个严重的问题。我科收治了76例特发性垂体性侏儒症,以下对其发病机理作一初步探讨和分析。 我们对76例特发性垂体性侏儒症患者从遗传学、染色体、父母血缘和分娩方式等方面进行了专门调查,前三方面未发现异常,而分娩方式则多为臀位产和部分横位产、立位产,78%出生时有缺氧、呼吸障碍、紫绀等产期损伤,且臂位、立位、高位产钳助产的小儿中,垂体性侏儒的发病率较高。在我们诊治的76例垂体性侏儒症中除4例产位不详,臀(立)位产42例、横位4例、高位产钳助产4例,占总数的65.79%,与国外学者Berich统计报道的
According to the International Year of Medicine statistics, the incidence of short stature caused by heredity and endocrinology is 43 per 10,000. At present, there are millions of such patients in our country and it is obviously a serious problem to improve the national physiological quality. My department treated 76 cases of idiopathic pituitary dwarfism, the following for its pathogenesis for a preliminary discussion and analysis. We conducted a special survey of 76 idiopathic pituitary dwarfism patients from the aspects of genetics, chromosomes, parentage, and mode of delivery, with no abnormalities found in the first three aspects, while the mode of delivery was mostly breech and partial horizontal Birth, standing production, 78% were born hypoxia, respiratory disorders, cyanosis and other production injury, and the arm, the position, high forceps in children, the incidence of pituitary dwarf higher. In our diagnosis and treatment of 76 cases of pituitary dwarfism in addition to 4 cases of unknown birth position, hip production (42 cases), horizontal in 4 cases, high forceps in 4 cases, accounting for 65.79% of the total, with foreign scholars Berich statistics Reported