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目的探讨分析胃黏膜相关淋巴组织(MALT)淋巴瘤的临床病理学特点。方法选取我院及合作医院(苏大附二院,昆山一院)2009年8月~2013年8月收治的40例MALT淋巴瘤患者回顾性分析。结果 40例患者临床及内镜下表现无显著差异,幽门螺杆菌(Hp)检测显示感染37例,感染率高达92.5%,胃镜下病灶主要发于胃窦及胃体,首次患者在胃镜下活检阳性较少18例,几率仅45%。结论 MALT淋巴瘤临床表现无特异,在胃镜下表现则多样,提高医师对本症的认知、胃镜下活检阳性率及对活检做免疫组织化学染色是MALT淋巴瘤症诊断的关键。
Objective To investigate the clinicopathological features of gastric mucosa-associated lymphoid tissue (MALT) lymphoma. Methods A retrospective analysis of 40 patients with MALT lymphoma admitted to our hospital and affiliated hospital (Second Affiliated Hospital of Suzhou Second Affiliated Hospital, Kunshan First Hospital) from August 2009 to August 2013 was conducted. Results There were no significant differences in clinical and endoscopic findings among the 40 patients. Helicobacter pylori (Hp) test showed 37 cases were infected, the infection rate was as high as 92.5%. The lesions under gastroscope mainly occurred in gastric antrum and gastric body. The first patient underwent endoscopic biopsy Less positive in 18 cases, the probability of only 45%. Conclusion The clinical manifestations of MALT lymphomas are nonspecific, and their manifestations are diverse under endoscopy. Improving the physician ’s cognition of the disease, the positive rate of endoscopic biopsy and the immunohistochemical staining of the biopsy are the key points in the diagnosis of MALT lymphoma.