【摘 要】
:
We theoretically investigated negative entropy S of biopolymer which passes through a nanometer pore(such as α-hemolysin), especially entering process and esca
【机 构】
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College of Life Sciences and Bioengineering,Institute of Animal Sciences
【基金项目】
:
National Infrastructure of Natural Science and Technology Program;国家自然科学基金;the Chinese National Science and Technology Pillar Program for the Eleventh Five-year Plan
论文部分内容阅读
We theoretically investigated negative entropy S of biopolymer which passes through a nanometer pore(such as α-hemolysin), especially entering process and escaping process, on the basis of which we also studied biopolymer entering-pore time τ_(ent), biopolymer entering mean velocity v_(ent), biopolymer escaping-pore time τ_(esc), and biopolymer escaping mean velocity v_(esc), respectively. Our results illustrate that the entering and escaping processes of biopolymer depend on its negative entropy, and entering process is more difficult than escaping process for biopolymer translocation. This tremendous difference between the two processes will offer a useful engineering hint for single macromolecule identification.
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