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目的:观察饮食干预法治疗老年2型糖尿病合并痛风临床效果。方法:选择老年2型糖尿病合并痛风72例,随机分为观察组和对照组治疗的各36例。对照组采用常规药物治疗,给予糖尿病饮食;观察组在对照组治疗的基础上,增加饮食干预。40天后,比较两组血糖(PG)、血尿酸(UA)水平和住院时间及肾功能等指标。结果:干预后,观察组空腹血糖(FBG)≤6.1mmol/L 30例(83.3%),餐后2h血糖(P2hPG)≤11.1mmol/L 28例(77.8%);对照组为15例(41.7%)和16例(44.4%)。两组比较,差异显著(P<0.05)。观察组住院时间(30±1.1)天,对照组为(41±1.2)天;两组比较,差异显著(P<0.05)。观察组血UA降至正常水平时间(11±1.0)天,对照组为(20±0.9)天;两组比较,差异显著(P<0.05)。治疗后,两组血尿素氮(BUN)、肌酐(Cr)和半胱氨酸蛋白酶C(CysC)等肾功能指标变化差异非常显著(P<0.01)。结论:常规药物治疗加饮食干预治疗2型糖尿病合并痛风效果优于单纯药物治疗。
Objective: To observe the clinical effect of diet intervention in the treatment of elderly type 2 diabetes with gout. Methods: A total of 72 elderly patients with type 2 diabetes mellitus and gout were randomly divided into observation group (36 cases) and control group (36 cases). The control group was treated with conventional drugs, giving diabetic diet; observation group in the control group based on the treatment, increase diet intervention. After 40 days, the levels of blood glucose (PG), serum uric acid (UA) and length of hospital stay and renal function were compared. Results: After intervention, the observation group had fasting blood glucose (FBG) ≤6.1mmol / L in 30 patients (83.3%), postprandial 2h blood glucose (P2hPG) ≤11.1mmol / L in 28 patients (77.8% %) And 16 cases (44.4%). The difference between the two groups was significant (P <0.05). The length of stay in the observation group was (30 ± 1.1) days and that in the control group was (41 ± 1.2) days. The difference between the two groups was significant (P <0.05). The blood UA in the observation group decreased to the normal level (11 ± 1.0) days and that in the control group was (20 ± 0.9) days. There was significant difference between the two groups (P <0.05). After treatment, the changes of renal function index such as BUN, Cr and CysC were significant difference (P <0.01). Conclusion: The effect of conventional medical therapy plus diet intervention on type 2 diabetes mellitus combined with gout is better than that of simple drug therapy.