论文部分内容阅读
目的:探讨高胰岛素血症(HIS)、胰岛素抵抗(IR)与老年脑梗死发病的关系.方法:测定34例60岁以上老年脑梗死患者和20名正常人的葡萄糖耐量试验(OGTT)后血糖、胰岛素及其曲线下面积(AUC)和胰岛素/血糖、血脂变化.结果:脑梗死组糖负荷后血糖、胰岛素、胰岛素/血糖、AUC以及总胆固醇明显高于对照组,胰岛素敏感性指数(ISI)及HDL－C明显低于对照组,糖负荷后1小时、2小时胰岛素及其AUC与舒张压呈正相关,甘油三酯、总胆固醇与空腹和1小时胰岛素呈正相关.结论:老年脑梗死存在HIS和IR,并可能通过影响血压和脂质代谢等而促进脑梗死的发病.“,”Objective: To study the relationship among the hyperinsulinemia(HIS), insulin resistance(IR) and cerebral infarction. Methods: Oral glucose tolerance test(OGTT) and insulin release test were performed, and changes in plasma glucose and insulin level, area under the curve (AUC) of insulin, insulin/glucose ratio and lipid profile in 34 elderly patients (equal or more than sixty old) with cerebral infarction were compared with those in 20 normal control subjects . Results...