ⅡⅢ、 期结肠癌具高危机肿瘤复发 ,应属辅助治疗的对象。由于 50 %复发是肝转移和 2 0 %～ 50 %发生在腹膜 ,应用门静脉输注或腹腔内灌注 5-氟尿嘧啶 (5-Fu)以获得局部区域性化疗 ,使区域性和肝内 5- Fu浓度增高而毒性减少。为了阐明腹腔内辅助化疗的效果 ,作者分析 9家单位共 Ⅱ Ⅲ, stage colon cancer with high-risk tumor recurrence should be the object of adjuvant therapy. Since 50% of relapses are liver metastases and 20% to 50% occur in the peritoneum, topical chemotherapy is achieved by intra-peritoneal infusion of 5-fluorouracil (5-Fu) via portal vein infusion or intraperitoneal injection of 5-Fu Increased concentration and reduced toxicity. To clarify the efficacy of intraperitoneal adjuvant chemotherapy, the authors analyzed a total of 9 units