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经抗酸剂治愈的消化性溃疡在停药后极易复发，根治溃疡中的幽门螺杆菌感染可减少复发。单一或二联用药因根治率低于90％而不适用。以钦剂为基础的三联用药（铋剂＋四环素＋甲硝唑）在菌株敏感及病人配合的情况下，根治率可达95％以上，但副作用较多。由奥美拉唑与两种抗生素（克拉霉素和／成阿莫西林和／或甲硝唑）组成的三联用药或与以铋剂为基础的三联组成的四联用药交有效且疗程更短，疗效不受菌株对咪唑类药物耐药的影响。本文综述了有关根治消化性溃疡中幽门螺杆菌感染的研究进展。
Peptic ulcer healed by antacids is easy to relapse after stopping drug treatment, Helicobacter pylori infection in root ulcer can reduce recurrence. Single or two drugs because the cure rate is less than 90% and not applicable. In the triadimefon (bismuth + tetracycline + metronidazole) in the case of sensitive strains and patients, the cure rate of up to 95%, but more side effects. Triple therapy with omeprazole and two antibiotics (clarithromycin and / or amoxicillin and / or metronidazole) or quadruplets with bismuth-based triad is effective and short-course , The effect is not affected by the strains of imidazole drug resistance. This review summarizes the research progress on Helicobacter pylori infection in the treatment of peptic ulcer.