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类胰升血糖素肽-1(Ghuca Con-like peptide,GLP-1)是一种作用很强的肠道肽类激素,这种激素补充了传统的肠促胰岛素的标准。是肠-胰岛轴中涉及葡萄糖自身平衡的一种有效的激素介质。是肠道胰升血糖素前体翻译后修饰的产物。由肠道内分泌细胞分泌,主要分布在肠管远端,并在餐后释放入血,通过与特异性GLP-1受体结合发挥其生物学作用。是一种能够抑制胰升血糖索分泌的肠促胰岛素。 一、对胰腺的作用
Ghuca Con-like peptide (GLP-1) is a potent gut peptide hormone that complements the traditional incretin standard. Is an effective hormonal mediator in the gut-islet axis that involves the glucose self-balance. Is a product of posttranslational modification of gut glucagon precursors. Secreted by intestinal endocrine cells, mainly in the distal bowel, and release into the blood after a meal, and through the specific GLP-1 receptor to play its biological role. Is a can inhibit glucocorticoid secretion of incretin. First, the role of the pancreas