最早认为克隆氏病是回肠末端的一种病变,后来认为该病可侵犯胃肠道任何部分。近来,已明确“克隆氏病”包括过去被认为克隆氏病的肠外系统并发症如唇、口腔、肛门、皮肤、肝脏、肌肉和骨骼。克隆氏病的某些肠外表现(如口腔和肛门)可比肠内病变早出现数年。外阴克隆氏病罕见,至今仅有少数病例报告。本文报道一位18岁克隆氏病的女性患者,仅表现外阴和会阴部损害而无胃肠道症状。病例报告:一位18岁阿拉伯女性患者因外阴和会阴部肿胀4个月住入以色列EMEK中心医院皮肤科 Crohn’s disease was first thought to be a lesion in the distal ileum that was later thought to invade any part of the gastrointestinal tract. Recently, it has been clarified that “Crohn’s disease” includes parenteral systemic complications such as lip, mouth, anus, skin, liver, muscle and bone that were previously thought to be Crohn’s disease. Some of the extraintestinal manifestations of Crohn’s disease (such as buccal and anal) can occur several years earlier than intestinal lesions. Vulvar Crohn’s disease rare, so far only a few cases reported. This article reports an 18-year-old female with Crohn’s disease who showed only lesions of the vulva and perineum without gastrointestinal symptoms. Case Report: An 18-year-old Arab woman who had swollen his vulva and perineum for 4 months was admitted to the dermatology department of the EMEK Central Hospital in Israel