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据研究,某种原因引起心房扩大时,血浆心房利钠肽(ANP)可以升高,如充血性心力衰竭,心房纤颤和房性心动过速等。心肌梗塞时由于急性心肌缺血损害了心室机能,推测可能有较多的 ANP 自扩大的心房释放。为了验证这一假设,作者观察了4例发病2h 以内入院的急性前壁心肌梗塞患者的血浆 ANP 变化。每隔30min 自患者前臂静脉采血1次,以放射免疫法测定血浆 ANP 浓度。
According to the study, atrial enlargement of a cause, plasma atrial natriuretic peptide (ANP) can be elevated, such as congestive heart failure, atrial fibrillation and atrial tachycardia and so on. Myocardial infarction due to acute myocardial ischemia damage ventricular function, suggesting that there may be more self-expanding ANP release of the atrium. To test this hypothesis, the authors observed changes in plasma ANP levels in 4 patients with acute anterior myocardial infarction admitted to hospital within 2h. Blood samples were obtained from the forearm vein of patients every 30 minutes, and plasma ANP concentration was determined by radioimmunoassay.